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X LINKED PHOSPHATE REGULATING ENDOPEPTIDASE HOMOLOG
Descriptors Found:
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DeCS
Descriptor
English
:
PHEX Phosphate Regulating Neutral Endopeptidase
Descriptor
Spanish
:
endopeptidasa neutra reguladora de fosfato PHEX
Descriptor
Portuguese
:
Endopeptidase Neutra Reguladora de Fosfato PHEX
Synonyms
English
:
PEX Phosphate Regulating Neutral Endopeptidase
Phosphate Regulating Endopeptidase Homolog, X Linked
Phosphate Regulating Endopeptidase Homolog, X-Linked
Phosphate Regulating Neutral Endopeptidase
X Linked Phosphate Regulating Endopeptidase Homolog
X-Linked Phosphate Regulating Endopeptidase Homolog
Tree Number:
D08.811.277.656.300.480.616
D08.811.277.656.675.374.616
D12.776.395.550.611
D12.776.543.550.607
Definition
English
:
A membrane-bound metalloendopeptidase that may play a role in the degradation or activation of a variety of
PEPTIDE HORMONES
and
INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS
. Genetic
mutations
that result in loss of function of this protein are a cause of HYPOPHOSPHATEMIC
RICKETS
, X-LINKED DOMINANT.
Entry Combination - descr/qualif
English
:
PHEX Phosphate Regulating Neutral Endopeptidase
/
deficiency
use
Familial Hypophosphatemic Rickets
History Note
English
:
2007(1995)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52242
Unique Identifier:
D053402
Occurrence in VHL
:
Similar:
DeCS